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If you suddenly stop taking Hydroxyurea , you may experience WITHDRAWAL symptoms including anxiety;
Hydroxyurea may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE.
Hydroxyurea has not been shown to cause histamine release. At therapeutic doses, Hydroxyurea has no effect on heart rate,
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A single i.m. dose of Hydroxyurea is useful pre-treatment to minimize the risk of acid aspiration during operation,
Hydroxyurea is associated with craving and tolerance development.
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Hydroxyurea is extensively metabolized by a number of pathways, including CYP2D6 and CYP3A4,
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This is known as physical DEPENDENCE. If you suddenly stop taking Hydroxyurea , you may experience WITHDRAWAL symptoms including anxiety;
Hydroxyurea has not been shown to cause histamine release. At therapeutic doses, Hydroxyurea has no effect on heart rate, left-ventricular function or cardiac index.
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Hydroxyurea was not mutagenic in the following assays: Ames Salmonella microsomal activation test,
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Hydroxyurea may not work as well and may require higher doses to obtain.
For Hydroxyurea, the following should be considered:The suitability of Hydroxyurea suppositories for inclusion in our hospital formulary for the treatment of mild to moderate post-operative pain was evaluated.
Hydroxyurea is a centrally acting synthetic opioid analgesic.
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Hydroxyurea may rarely be habit forming. Hydroxyurea should be avoided in patients with a history of opiate addiction or hypersensitivity to opiate medications.
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This indicates that Hydroxyurea slightly decreases the precision of thermoregulatory control in addition to reducing the setpoint.
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since observed maximal placoncentrations after multiple oral doses are higher than expected based on single-dose data.
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The volume of distribution of Hydroxyurea was 2.6 and 2.9 liters/kg in male and female subjects, respectively,
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Hydroxyurea can impair thinking and the physical abilities required for driving or operating machinery. Hydroxyurea should be avoided in patients intoxicated with alcohol,
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The volume of distribution of Hydroxyurea was 2.6 and 2.9 liters/kg in male and female subjects, respectively,
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